Palms (rare but possible)

Under the fingernails (called subungual melanoma)

How to Tell If a Dark Spot on Your Hand Might Be Melanoma

Use the ABCDE Rule to assess the spot:

A (Asymmetry): One half of the spot doesn’t match the other
B (Border): Edges are irregular, ragged, or blurred
C (Color): Multiple colors (brown, black, red, blue, white)
D (Diameter): Larger than 6 mm (about a pencil eraser)
E (Evolving): Changing in size, shape, or color over time

Other red flags:

A spot that itches, bleeds, or crusts

A new mole or spot appearing in adulthood

A dark line or spot under a fingernail (especially if it grows or spreads)

A spot that looks very different from other moles (the “ugly duckling”)